Drug points: Antibody deficiency associated with carbamazepine
نویسندگان
چکیده
منابع مشابه
Pulmonary eosinophilia associated with carbamazepine.
An 8 year old girl treated with carbamazepine developed eczema, wheeze, and evidence of pulmonary eosinophilia. Single dose challenge confirmed allergy to this drug. This reaction should be considered in patients being treated with carbamazepine who develop respiratory symptoms.
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An I1-year-old boy presented with a 1-year history of attacks of unconsciousness lasting about 10 min. There were no tonic or clonic movements. Some attacks were photically induced. An electroencephalogram was abnormal with excessive slow wave activity over the left cerebral hemisphere. He was treated with carbamazepine (5-7 mg/kg) twice daily. One month later he presented with an 8-hr history ...
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Ig class-switch recombination (Ig-CSR) deficiencies are rare primary immunodeficiencies characterized by defective switched isotype (IgG/IgA/IgE) production. Depending on the molecular defect, defective Ig-CSR may also be associated with impaired somatic hypermutation (SHM) of the Ig V regions. Although the mechanisms underlying Ig-CSR and SHM in humans have been revealed (at least in part) by ...
متن کاملCarbamazepine-induced IgG1 and IgG2 deficiency associated with B cell maturation defect
This paper presents the first case of asymptomatic IgG1 and IgG2 deficiency induced by carbamazepine (CBZ). The patient has remained asymptomatic since CBZ was started because IgM reduced only transiently, IgA decreased but remained within the normal range, and the specific antibodies to organisms having capsular polysaccharide antigens were not defective in this case. Analysis of membrane surf...
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ژورنال
عنوان ژورنال: BMJ
سال: 2002
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.325.7374.1213